Rosacea yanayi ne da aka fi sani da jajayen fuska da kumburi.Yana shafar kusan kashi 5% na al'ummar duniya, kuma ko da yake an san musabbabin hakan, ba a san su sosai ba.Ana la'akari da yanayin fata na dogon lokaci, kuma yawanci yana shafar matan Turai / Caucasian fiye da shekaru 30. Akwai nau'i-nau'i daban-daban na rosacea kuma yana iya shafar kowa.
Ana yin nazari sosai game da maganin jan haske don abubuwa kamar warkar da fata, kumburi gaba ɗaya, collagen a cikin fata, da yanayin fata iri-iri kamar kuraje.A dabi'a sha'awar ta girma wajen amfani da hasken ja don rosacea.A cikin wannan labarin za mu dubi ko ko a'a farfasa haske (wanda kuma aka sani da photobiomodulation, LED far, Laser therapy, sanyi Laser, haske far, LLLT, da dai sauransu) zai iya taimaka wajen bi da rosacea.
Nau'in Rosacea
Duk wanda ke da rosacea yana da ɗan bambanci daban-daban kuma na musamman.Yayin da ake danganta rosacea tare da jajayen fuska a kusa da hanci da kuma kunci, akwai wasu alamomi daban-daban waɗanda za a iya rushewa kuma a rarraba su zuwa cikin 'subtypes' rosacea:
Subtype 1, wanda ake magana da shi da 'Erythematotelangiectatic Rosacea' (ETR), shine rosacea stereotypical wanda ke gabatar da ja ta fuska, kumburin fata, tasoshin jini kusa da saman da lokutan ruwa.Erythema ya fito ne daga kalmar Helenanci erythros, wanda ke nufin ja - kuma yana nufin jan fata.
Subtype 2, Acne rosacea (sunan kimiyya - papulopustular), ita ce rosacea inda ake hada fata ja tare da kuraje masu tsayi ko tsaka-tsalle-kamar fashewa (pustules da papules, ba baki ba).Wannan nau'in na iya haifar da ƙonawa ko jin zafi.
Subtype 3, AKA phymatous rosacea ko rhinophyma, wani nau'i ne na rosacea da ba kasafai ba kuma ya ƙunshi sassan fuskar da ke ƙara girma - yawanci hanci (hanci dankalin turawa).Ya fi kowa a cikin mazan maza kuma yawanci yana farawa azaman wani nau'in rosacea.
Subtype 4 shine rosacea na ido, ko rosacea na ido, kuma ya ƙunshi idanu masu zubar da jini, idanu masu ruwa, jin wani abu a cikin ido, konewa, ƙaiƙayi da kumbura.
Sanin nau'ikan nau'ikan rosacea yana da mahimmanci a tantance idan da gaske kuna da ita.Idan ba a yi wani abu don magance rosacea ba, yana ƙara tsananta a kan lokaci.An yi sa'a, dacewar maganin hasken ja don magance rosacea baya canzawa tare da nau'in subtype.Ma'ana ka'idar maganin hasken ja iri ɗaya zata yi aiki ga kowane nau'i-nau'i.Me yasa?Bari mu dubi abubuwan da ke haifar da rosacea.
Ainihin Dalilin Rosacea
(...kuma me yasa maganin haske zai iya taimakawa)
Shekaru da yawa da suka gabata, an fara yarda cewa rosacea shine sakamakon kamuwa da cuta.Kamar yadda maganin rigakafi (ciki har da tetracycline) yayi aiki zuwa wani mataki don sarrafa alamun bayyanar, ya zama kamar kyakkyawan ka'idar…. amma da sauri an gano cewa babu kwayoyin cuta a ciki.
Yawancin likitoci da masana kan rosacea kwanakin nan za su gaya muku cewa rosacea abin mamaki ne kuma babu wanda ya gano dalilin.Wasu za su nuna Demodex mites a matsayin dalilin, amma kusan kowa yana da waɗannan kuma ba kowa yana da rosacea ba.
Sa'an nan a maimakon haka za su jera 'masu tayar da hankali' daban-daban a maimakon dalilin, ko kuma su ba da shawarar cewa kwayoyin halitta da abubuwan da ba a bayyana ba su ne sanadin.Ko da yake kwayoyin halitta ko abubuwan epigenetic na iya sa wani ya sami rosacea (dangi ga wani mutum), ba su ƙayyade shi ba - ba su ne dalilin ba.
Abubuwa daban-daban ba shakka suna ba da gudummawa ga tsananin alamun rosacea (caffeine, kayan yaji, wasu abinci, sanyi/zafi, damuwa, barasa, da sauransu), amma kuma ba su ne tushen tushen ba.
To menene?
Alamun dalili
Alamar farko ga dalilin ita ce gaskiyar cewa rosacea yakan tasowa bayan shekaru 30. Wannan shine shekarun da alamun farko na tsufa suka bayyana.Yawancin mutane za su lura da gashin kansu na farko da launin toka na farko da ƙananan wrinkles na farko a kusa da wannan shekarun.
Wani ma'ana shine gaskiyar cewa maganin rigakafi yana taimakawa wajen sarrafa alamun bayyanar cututtuka - ko da yake babu ainihin kamuwa da cuta (alama: maganin rigakafi na iya samun tasirin maganin kumburi na gajeren lokaci).
Ruwan jini zuwa fata da rosacea ta shafa ya ninka sau 3 zuwa 4 fiye da fata ta al'ada.Wannan tasirin hyperemia yana faruwa lokacin da kyallen takarda da sel ba su iya fitar da iskar oxygen daga jini.
Mun san cewa rosacea ba kawai batun kwaskwarima ba ne, amma ya ƙunshi manyan canje-canjen haɓakar fibrotic ga fata (saboda haka hancin dankalin turawa a cikin nau'in nau'in 3) da haɓakar jijiyoyin jini (saboda haka veins / flushing).Lokacin da waɗannan ainihin alamun bayyanar cututtuka suka faru a wasu wurare a cikin jiki (misali fibroids na uterine) suna ba da izinin bincike mai mahimmanci, amma a cikin fata an watsar da su a matsayin al'amurran kwaskwarima don ' sarrafa su' ta hanyar ' guje wa abubuwan da ke jawo ', kuma daga baya har ma da tiyata don cire fata mai kauri. .
Rosacea lamari ne mai mahimmanci saboda tushen dalilin shine tsarin ilimin lissafin jiki mai zurfi a cikin jiki.Halin ilimin lissafin jiki wanda ke haifar da waɗannan canje-canjen fata ba kawai yana shafar fata ba - yana rinjayar duk jikin ciki ma.
Ana iya lura da zubar da ruwa, hawan jini mai girma / masu cin zarafi da kuma kauri na fata a cikin rosacea, saboda yana bayyana a cikin fata - saman jiki.A wata hanya, yana da albarka don samun alamun rosacea, domin yana nuna maka cewa wani abu ba daidai ba ne a ciki.Asarar gashi na ƙirar namiji abu ne mai kama da shi a cikin abin da yake nuna rashin daidaituwa na hormonal.
Mitochondrial lahani
Duk abubuwan lura da ma'auni game da rosacea suna nuna matsalolin mitochondrial a matsayin tushen tushen rosacea.
Mitochondria ba zai iya amfani da iskar oxygen yadda ya kamata lokacin da suka lalace.Rashin iya yin amfani da iskar oxygen yana ƙara yawan jini zuwa nama.
Mitochondria yana samar da lactic acid lokacin da ba za su iya samun kuma amfani da oxygen ba, wanda ke haifar da vasodilation nan da nan da ci gaban fibroblasts.Idan wannan matsala ta tsawaita na wani lokaci, sabbin hanyoyin jini sun fara girma.
Daban-daban na hormonal da muhalli na iya taimakawa wajen aikin mitochondrial maras kyau, amma a cikin mahallin jan haske mai haske, mafi mahimmancin tasiri shine daga kwayar halitta mai suna Nitric Oxide.
Red Light Therapy da Rosacea
Babban ka'idar da ke bayanin tasirin maganin hasken ya dogara ne akan kwayar halitta da ake kira Nitric Oxide (NO).
Wannan kwayar halitta ce mai iya yin tasiri daban-daban a jiki, kamar hana samar da makamashi, vasodilation / fadada hanyoyin jini, da sauransu.Babban abin da muke sha'awar ilimin hasken haske shine wannan NO yana ɗaure a wani maɓalli a cikin sarkar jigilar lantarki ta mitochondrial, dakatar da kwararar kuzari.
Yana toshe matakan ƙarshe na amsawar numfashi, don haka yana hana ku samun babban ɓacin kuzari (ATP) da kowane carbon dioxide daga glucose/oxygen.Don haka lokacin da mutane suka sami raguwar adadin kuzari na dindindin yayin da suke tsufa ko kuma suna fuskantar lokutan damuwa/yunwa, wannan NO yawanci ke da alhakin.Yana da ma'ana lokacin da kuka yi tunani game da shi, a cikin yanayi ko cikin rayuwa, kuna buƙatar wata hanyar da za ta rage ƙimar ku a lokutan ƙarancin wadatar abinci / kalori.Ba shi da ma'ana sosai a duniyar zamani inda NO matakan da za a iya tasiri ta takamaiman nau'ikan amino acid a cikin abinci, gurɓataccen iska, mold, sauran abubuwan abinci, hasken wucin gadi, da sauransu. Rashin iskar carbon dioxide a jikinmu kuma. ramp up kumburi.
Maganin haske yana haɓaka samar da makamashi (ATP) da carbon dioxide (CO2).Hakanan CO2 yana hana cytokines pro-inflammatory daban-daban da prostaglandins.Don haka maganin haske yana rage yawan kumburi a cikin jiki / yanki.
Don rosacea mabuɗin ɗaukar hoto shine cewa hasken haske zai rage kumburi da ja a cikin yanki, kuma yana warware matsalar ƙarancin amfani da iskar oxygen (wanda ya haifar da haɓakar jini da haɓakar fibroblast).
Takaitawa
Akwai daban-daban subtypes da bayyanuwar rosacea
Rosacea alama ce ta tsufa, kamar wrinkles da furfura
Tushen tushen rosacea shine rage aikin mitochondrial a cikin sel
Maganin hasken ja yana mayar da mitochondria kuma yana rage kumburi, yana hana rosacea
Lokacin aikawa: Satumba-30-2022