Cutar Alzheimer, wata cuta mai ci gaba da shafar jijiyoyin kwakwalwa, tana bayyana ta hanyar alamu kamar rashin tunawa da abubuwa, rashin ƙarfin gani, rashin ƙarfin gani, da kuma rashin aikin zartarwa. A al'ada, marasa lafiya sun dogara da magunguna don rage alamun cutar. Duk da haka, saboda ƙuntatawa da yuwuwar illolin waɗannan magunguna, masu bincike sun mayar da hankalinsu ga maganin phototherapy wanda ba shi da tasiri, wanda ya cimma manyan nasarori a cikin 'yan shekarun nan.
Kwanan nan, wata ƙungiya ƙarƙashin jagorancin Farfesa Zhou Feifan daga Kwalejin Injiniyan Halittu ta Jami'ar Hainan ta gano cewa maganin phototherapy na transcranial ba tare da taɓawa ba zai iya rage alamun cututtuka da kuma haɓaka ƙwarewar fahimta a cikin beraye masu tsufa da waɗanda ke fama da cutar Alzheimer. Wannan binciken mai ban mamaki, wanda aka buga a cikin mujallar Nature Communications, yana ba da wata dabara mai kyau don magance cututtukan jijiyoyi.
Fahimtar Cututtukan Cutar Alzheimer
Har yanzu ba a san ainihin musabbabin cutar Alzheimer ba, amma ana siffanta shi da rashin daidaituwar tarin furotin na beta-amyloid da kuma haɗakar neurofibrillary, wanda ke haifar da rashin aiki a jijiyoyi da kuma raguwar fahimta. Kwakwalwa, a matsayinta na mafi yawan sassan jiki masu aiki a fannin metabolism, tana samar da sharar metabolism mai yawa yayin aikin jijiyoyi. Tarin wannan sharar da ya wuce kima na iya lalata jijiyoyi, wanda hakan ke haifar da cirewa cikin inganci ta hanyar tsarin lymphatic.
Jijiyoyin lymphatic na meningeal, waɗanda suke da mahimmanci ga tsarin jijiyoyi na tsakiya, suna taka muhimmiyar rawa wajen kawar da sunadaran beta-amyloid masu guba, sharar metabolism, da kuma daidaita ayyukan garkuwar jiki, wanda hakan ya sanya su zama abin da za a yi wa magani.
Tasirin Phototherapy akan Alzheimer's
Tawagar Farfesa Zhou ta yi amfani da na'urar laser mai karfin nm 808 kusa da infrared na tsawon makonni hudu na gyaran fuska ta transcranial ba tare da taɓawa ba ga beraye tsofaffi da kuma waɗanda ke fama da cutar Alzheimer. Wannan maganin ya inganta aikin ƙwayoyin endothelial na meningeal lymphatic, ya inganta magudanar ruwa ta lymphatic, kuma a ƙarshe ya rage alamun cututtuka da kuma inganta ayyukan fahimta a cikin beraye.
Inganta Aikin Jijiyoyi ta hanyar Phototherapy
Phtotherapy na iya inganta da kuma inganta aikin jijiyoyi ta hanyoyi daban-daban. Misali, tsarin garkuwar jiki yana taka muhimmiyar rawa a cikin cututtukan Alzheimer. Binciken da aka yi kwanan nan ya nuna cewa hasken laser kore mai tsawon nm 532 na iya haɓaka aikin ƙwayoyin garkuwar jiki, yana haifar da hanyoyin da ke cikin jijiyoyin tsakiya masu zurfi, inganta ciwon hauka na jijiyoyin jini, da kuma haɓaka yanayin kwararar jini da alamun asibiti a cikin marasa lafiya da Alzheimer. Hasken laser na jijiyoyin jini na farko ya nuna ci gaba mai mahimmanci a cikin dankowar jini, dankowar plasma, tarin ƙwayoyin jinin ja, da gwaje-gwajen neuropsychological.
Maganin haske ja da infrared (photobiomodulation) da aka yi amfani da shi a wuraren jiki na gefe (baya da ƙafafu) na iya kunna hanyoyin kariya na ƙwayoyin rigakafi ko ƙwayoyin tushe, wanda ke ba da gudummawa ga rayuwar jijiyoyi da kuma bayyanar kwayoyin halitta masu amfani.
Lalacewar iskar oxygen shima muhimmin tsari ne na cututtukan da ke haifar da cutar Alzheimer. Bincike ya nuna cewa hasken ja na iya ƙara yawan ayyukan ATP na ƙwayoyin halitta, yana haifar da canjin metabolism daga glycolysis zuwa aikin mitochondrial a cikin ƙwayoyin kumburi da oligomeric beta-amyloid ke shafar, yana haɓaka matakan ƙwayoyin cuta masu hana kumburi, rage cytokines masu hana kumburi, da kuma kunna phagocytosis don hana mutuwar jijiyoyi.
Inganta faɗakarwa, wayar da kan jama'a, da kuma kulawa mai ɗorewa wata hanya ce mai kyau don inganta rayuwar marasa lafiya da ke fama da cutar Alzheimer. Masu bincike sun gano cewa fallasa ga hasken shuɗi mai gajeren zango yana da tasiri mai kyau ga aikin fahimta da kuma daidaita motsin rai. Hasken hasken shuɗi na iya haɓaka ayyukan da'irar jijiyoyi, yana tasiri ga ayyukan acetylcholinesterase (AchE) da choline acetyltransferase (ChAT), ta haka yana inganta koyo da ƙwarewar ƙwaƙwalwa.
Kyakkyawan Tasirin Phototherapy akan Jijiyoyin Kwakwalwa
Wani bincike mai ƙarfi da aka gudanar ya tabbatar da tasirin phototherapy akan aikin ƙwayoyin kwakwalwa. Yana taimakawa wajen kunna hanyoyin kariya na ƙwayoyin rigakafi, yana haɓaka bayyanar kwayoyin halittar da ke rayuwa a cikin jijiyoyi, da kuma daidaita matakan iskar oxygen na mitochondrial. Waɗannan binciken sun kafa harsashi mai ƙarfi don aikace-aikacen phototherapy na asibiti.
Bisa ga waɗannan bayanai, Cibiyar Bincike ta Makamashi ta MERICAN, tare da haɗin gwiwar ƙungiyar Jamus da jami'o'i da yawa, bincike, da cibiyoyin kiwon lafiya, sun gudanar da wani bincike da ya shafi mutane 'yan shekara 30-70 masu ƙarancin fahimtar juna, raguwar ƙwaƙwalwa, raguwar fahimta da yanke hukunci, da kuma raguwar ƙwarewar koyo. Mahalarta sun bi ƙa'idodin abinci da salon rayuwa mai kyau yayin da ake yin maganin phototherapy a cikin ɗakin kula da lafiya na MERICAN, tare da nau'ikan magunguna da yawan da aka ɗauka daidai.
Bayan watanni uku na gwaje-gwajen ilimin halayyar ɗan adam, gwaje-gwajen yanayin kwakwalwa, da kuma kimanta fahimtar mutum, sakamakon ya nuna ci gaba mai mahimmanci a cikin maki na MMSE, ADL, da HDS tsakanin masu amfani da maganin phototherapy na ɗakin lafiya. Mahalarta taron sun kuma sami ƙarin kulawa ta gani, ingancin barci, da kuma raguwar damuwa.
Waɗannan binciken sun nuna cewa maganin phototherapy na iya zama maganin tallafi don daidaita ayyukan ƙwayoyin kwakwalwa, rage kumburin jijiyoyi da sauran cututtuka masu alaƙa, inganta fahimta, da haɓaka ƙwaƙwalwa. Bugu da ƙari, yana buɗe sabbin hanyoyi don maganin phototherapy ya rikide zuwa hanyar magani ta rigakafi.
